Affective disorders are associated with maladaptive emotion regulation strategies. In particular, the left more than the right ventrolateral prefrontal cortex (vlPFC) may insufficiently regulate emotion processing, e.g., in the amygdala. A double-blind cross-over study investigated NF-supported cognitive reappraisal training in major depression (
fMRI Neurofeedback-Enhanced Cognitive Reappraisal Training in Depression: A Double-Blind Comparison of Left and Right vlPFC Regulation
M. Keller, J. Zweerings, M. Klasen, M. Zvyagintsev, J. Iglesias, R. QuiƱones and K. Mathiak
Front Psychiatry 2021;12:715898.