Microvascular effects of oxygen and carbon dioxide measured by vascular occlusion test in healthy volunteers

Changes in near-infrared spectroscopy-derived regional tissue oxygen saturation (StO StO DS and RS remained constant during all applied conditions. AUC-H after hypoxia was smaller compared to hyperoxia (963 %sec vs hyperoxia 1702 %sec, P = 0.005), while there was no difference in AUC-H duration between hypoxia and baseline. The StO We conclude that in healthy volunteers at rest, common situations observed during anesthesia and intensive care such as exposure to hypoxia, hyperoxia, hypocapnia, or hypercapnia, did not affect peripheral tissue O This study represents a secondary analysis of an original study which has been registered at ClinicalTrials.gov nr: NCT02561052.