Modeling SARS-CoV-2 and Influenza Infections and Antiviral Treatments in Human Lung Epithelial Tissue Equivalents

H. Zarkoob, A. Allué-Guardia, Y. Chen, O. Jung, A. Garcia-Vilanova, M. Song, J. Park, F. Oladunni, J. Miller, Y. Tung, I. Kosik, D. Schultz, J. Yewdell, J. Torrelles, L. Martinez-Sobrido, S. Cherry, M. Ferrer and E. Lee

bioRxiv 2021.

DOI PMID Cited by ~7

Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is the third coronavirus in less than 20 years to spillover from an animal reservoir and cause severe disease in humans. High impact respiratory viruses such as pathogenic beta-coronaviruses and influenza viruses, as well as other emerging respiratory viruses, pose an ongoing global health threat to humans. There is a critical need for physiologically relevant, robust and ready to use,