Publications of Gertrude Nieuwenhuijs

Papers in international journals

  1. de Ramos MMA, Ricardo-da-Silva FY, Vidal-Dos-Santos M, Vos MJ, Ottens PJ, Nieuwenhuijs-Moeke GJ, et al. Evaluation of donor's hormonal profile according to sex and age. Front Physiol. 2025;16:1676624.
    Abstract DOI PMID
  2. Veenker CGH, Redzhebov BB, Hoeks SE, van Eijk LT, Struys MMRF, de Hon O, et al. Effects of growth hormone and anabolic steroids, in critically ill patients admitted to the intensive care unit: a systematic review and meta-analysis. Sci Rep. 2025;15(1):36856.
    Abstract DOI PMID
  3. van Koningsveld-Couperus BH, de Rooij T, van Meeteren NL, Preckel B, Hollmann MW, Nieuwenhuijs-Moeke GJ. Prehabilitation: A Catalyst for Transforming Toward Value-Based, Personalized Perioperative Health and Care. J Clin Med. 2025;14(19).
    Abstract DOI PMID
  4. Günkel PN, Yang S, Tuinhout RS, Luttik SJ, Hoffmann RF, Ottens PJ, et al. Optimizing Donor Kidneys During Normothermic Machine Perfusion With Sevoflurane: Design of a Research Model. Artif Organs. 2025.
    Abstract DOI PMID
  5. Huisman GJJ, Berger SP, Thyrrestrup PS, Hausken J, Veelo DP, Guirado L, et al. Propofol-based versus sevoflurane-based anaesthesia for deceased donor kidney transplantation: the VAPOR-2 study protocol for an international multicentre randomised controlled trial. BMJ Open. 2025;15(9):e098965.
    Abstract DOI PMID
  6. Tuinhout RS, Jongman RM, Nieuwenhuijs-Moeke GJ, Abdulahad WH, Struys MMRF, van Meurs M, et al. Effects of sevoflurane, propofol, remifentanil, and fentanyl on the endothelial proinflammatory response: an in vitro exploratory study. Can J Anaesth. 2025;72(8):1291-1304.
    Abstract DOI PMID
  7. Gartzke LP, de Boer TH, Wolfswinkel SSM, Wink SE, Kalashnik R, van Buiten A, et al. Iron chelation prior to static cold storage decreases lipid peroxidation and improves gluconeogenesis during NMP in isolated porcine kidneys. Biomed Pharmacother. 2025;189:118343.
    Abstract DOI PMID
  8. Brattinga B, Huang H, Maslau S, Thorne AM, Hunter J, Knight S, et al. Effect of a Laparoscopic Donor Nephrectomy in Healthy Living Kidney Donors on the Acute Phase Response Using Either Propofol or Sevoflurane Anesthesia. Int J Mol Sci. 2025;26(11).
    Abstract DOI PMID
  9. Quint EE, Westenberg LB, Nieuwenhuijs-Moeke GJ, van den Broek EAN, Zorgdrager M, Viddeleer AR, et al. Analyzing body composition in living kidney donors: impact on post-transplant kidney function. Front Nephrol. 2024;4:1467669.
    Abstract DOI PMID Cited by ~1
  10. Nielsen MB, Krogstrup NV, Nieuwenhuijs-Moeke GJ, Oltean M, Dor FJMF, Jespersen B, et al. Correction: P-NGAL Day 1 predicts early but not one year graft function following deceased donor kidney transplantation-The CONTEXT study. PLoS One. 2024;19(5):e0304722.
    Abstract DOI PMID
  11. Driessens H, Wijma AG, Buis CI, Nijkamp MW, Nieuwenhuijs-Moeke GJ, Klaase JM. Author response to: Comment on: Prehabilitation: tertiary prevention matters. Br J Surg. 2024;111(5).
    DOI PMID Cited by ~1
  12. de Boer SE, Knobbe TJ, Kremer D, van Munster BC, Nieuwenhuijs-Moeke GJ, Pol RA, et al. Kidney Transplantation Improves Health-Related Quality of Life in Older Recipients. Transpl Int. 2024;37:12071.
    Abstract DOI PMID Cited by ~16
  13. Stern M, Kok WF, Doorduin J, Jongman RM, Jainandunsing J, Nieuwenhuijs-Moeke GJ, et al. Mild and deep hypothermia differentially affect cerebral neuroinflammatory and cold shock response following cardiopulmonary bypass in rat. Brain Behav Immun. 2024;119:96-104.
    Abstract DOI PMID Cited by ~2
  14. Brattinga B, Plas M, Spikman JM, Rutgers A, de Haan JJ, van der Wal-Huisman H, et al. The link between the early surgery-induced inflammatory response and postoperative cognitive dysfunction in older patients. J Am Geriatr Soc. 2024;72(5):1360-1372.
    Abstract DOI PMID Cited by ~6
  15. Driessens H, Wijma AG, Buis CI, Nijkamp MW, Nieuwenhuijs-Moeke GJ, Klaase JM. Prehabilitation: tertiary prevention matters. Br J Surg. 2024;111(3).
    DOI PMID Cited by ~8
  16. Steinkühler T, Yang S, Hu MA, Jainandunsing JS, Jager NM, Erasmus ME, et al. Ex Vivo Optimization of Donor Lungs with Inhaled Sevoflurane during Normothermic Ex Vivo Lung Perfusion (VITALISE): A Pilot and Feasibility Study in Sheep. Int J Mol Sci. 2024;25(4).
    Abstract DOI PMID Cited by ~1
  17. Hendriks S, Huisman MG, Stokmans SC, Plas M, van der Wal-Huisman H, van Munster BC, et al. The Association Between Intraoperative Compromised Intestinal Integrity and Postoperative Complications in Cancer Patients. Ann Surg Oncol. 2024;31(4):2699-2708.
    Abstract DOI PMID Cited by ~4
  18. Stern M, Nieuwenhuijs-Moeke GJ, Absalom A, van Leeuwen B, van der Wal-Huisman H, Plas M, et al. Association between anaesthesia-related factors and postoperative neurocognitive disorder: a post-hoc analysis. BMC Anesthesiol. 2023;23(1):368.
    Abstract DOI PMID Cited by ~8
  19. Kroneisl M, Spraakman NA, Koomen JV, Hijazi Z, Hoogstra-Berends FH, Leuvenink HGD, et al. Peri-Operative Kinetics of Plasma Mitochondrial DNA Levels during Living Donor Kidney Transplantation. Int J Mol Sci. 2023;24(17).
    Abstract DOI PMID Cited by ~4
  20. Schnider TW, Nieuwenhuijs-Moeke GJ, Beck-Schimmer B, Hemmerling TM. Pro-Con Debate: Should All General Anesthesia Be Done Using Target-Controlled Propofol Infusion Guided by Objective Monitoring of Depth of Anesthesia?. Anesth Analg. 2023;137(3):565-575.
    Abstract DOI PMID Cited by ~6
  21. Huisman GJJ, Spraakman NA, Koomen JV, Talsma AM, Pol RA, Berger SP, et al. Urinary Biomarkers in a Living Donor Kidney Transplantation Cohort-Predictive Value on Graft Function. Int J Mol Sci. 2023;24(6).
    Abstract DOI PMID Cited by ~2
  22. van den Berg TAJ, Nieuwenhuijs-Moeke GJ, Lisman T, Moers C, Bakker SJL, Pol RA. Pathophysiological Changes in the Hemostatic System and Antithrombotic Management in Kidney Transplant Recipients. Transplantation. 2023;107(6):1248-1257.
    Abstract DOI PMID Cited by ~7
  23. Spraakman NA, Coester AM, Bourgonje AR, Nieuwenhuijs VB, Sanders JF, Leuvenink HGD, et al. Systemic and Renal Dynamics of Free Sulfhydryl Groups during Living Donor Kidney Transplantation. Int J Mol Sci. 2022;23(17).
    Abstract DOI PMID Cited by ~4
  24. Bosch DJ, Nieuwenhuijs-Moeke GJ, van Meurs M, Abdulahad WH, Struys MMRF. Immune Modulatory Effects of Nonsteroidal Anti-inflammatory Drugs in the Perioperative Period and Their Consequence on Postoperative Outcome. Anesthesiology. 2022;136(5):843-860.
    Abstract DOI PMID Cited by ~42
  25. van den Berg TAJ, van den Heuvel MC, Wiersema-Buist J, Adelmeijer J, Nieuwenhuijs-Moeke GJ, Lisman T, et al. Aggravation of fibrin deposition and microthrombus formation within the graft during kidney transplantation. Sci Rep. 2021;11(1):18937.
    Abstract DOI PMID Cited by ~12
  26. Quint EE, Zogaj D, Banning LBD, Benjamens S, Annema C, Bakker SJL, et al. Frailty and Kidney Transplantation: A Systematic Review and Meta-analysis. Transplant Direct. 2021;7(6):e701.
    Abstract DOI PMID Cited by ~67
  27. Nieuwenhuijs-Moeke GJ, Bosch DJ, Leuvenink HGD. Molecular Aspects of Volatile Anesthetic-Induced Organ Protection and Its Potential in Kidney Transplantation. Int J Mol Sci. 2021;22(5).
    Abstract DOI PMID Cited by ~12
  28. Nieuwenhuijs-Moeke GJ, Nieuwenhuijs VB, Seelen MAJ, Berger SP, van den Heuvel MC, Burgerhof JGM, et al. Corrigendum to 'Propofol-based anaesthesia versus sevoflurane-based anaesthesia for living donor kidney transplantation: results of the VAPOR-1 randomized controlled trial' (Br J Anaesth 2017; 118: 720-32). Br J Anaesth. 2021;126(1):340-341.
    DOI PMID
  29. Quint EE, Schopmeyer L, Banning LBD, Moers C, Moumni ME, Nieuwenhuijs-Moeke GJ, et al. Transitions in frailty state after kidney transplantation. Langenbecks Arch Surg. 2020;405(6):843-850.
    Abstract DOI PMID Cited by ~25
  30. Nieuwenhuijs-Moeke GJ, Jainandunsing JS, Struys MMRF. Sevoflurane, a sigh of relief in COVID-19?. Br J Anaesth. 2020;125(2):118-121.
    DOI PMID Cited by ~31
  31. Nieuwenhuijs-Moeke GJ, Sanders JSF. Timing of renal replacement therapy in acute kidney injury: case closed?. Lancet. 2020;395(10235):1465-1467.
    DOI PMID Cited by ~2
  32. Nieuwenhuijs-Moeke GJ, Pischke SE, Berger SP, Sanders JSF, Pol RA, Struys MMRF, et al. Ischemia and Reperfusion Injury in Kidney Transplantation: Relevant Mechanisms in Injury and Repair. J Clin Med. 2020;9(1).
    Abstract DOI PMID Cited by ~240
  33. Nielsen MB, Krogstrup NV, Oltean M, Nieuwenhuijs-Moeke GJ, Dor FJMF, Birn H, et al. Remote ischaemic conditioning and early changes in plasma creatinine as markers of one year kidney graft function-A follow-up of the CONTEXT study. PLoS One. 2019;14(12):e0226882.
    Abstract DOI PMID Cited by ~16
  34. Nieuwenhuijs-Moeke GJ, Huijink TM, Pol RA, Moumni ME, Burgerhof JG, Struys MM, et al. Intraoperative Fluid Restriction is Associated with Functional Delayed Graft Function in Living Donor Kidney Transplantation: A Retrospective Cohort Analysis. J Clin Med. 2019;8(10).
    Abstract DOI PMID Cited by ~11
  35. Zorgdrager M, van Londen M, Westenberg LB, Nieuwenhuijs-Moeke GJ, Lange JFM, de Borst MH, et al. Chronic pain after hand-assisted laparoscopic donor nephrectomy. Br J Surg. 2019;106(6):711-719.
    Abstract DOI PMID Cited by ~20
  36. Nielsen MB, Krogstrup NV, Nieuwenhuijs-Moeke GJ, Oltean M, Dor FJMF, Jespersen B, et al. P-NGAL Day 1 predicts early but not one year graft function following deceased donor kidney transplantation - The CONTEXT study. PLoS One. 2019;14(2):e0212676.
    Abstract DOI PMID Cited by ~15
  37. van den Berg TAJ, Minnee RC, Lisman T, Nieuwenhuijs-Moeke GJ, van de Wetering J, Bakker SJL, et al. Perioperative antithrombotic therapy does not increase the incidence of early postoperative thromboembolic complications and bleeding in kidney transplantation - a retrospective study. Transpl Int. 2019;32(4):418-430.
    Abstract DOI PMID Cited by ~13
  38. Schopmeyer L, Moumni ME, Nieuwenhuijs-Moeke GJ, Berger SP, Bakker SJL, Pol RA. Frailty has a significant influence on postoperative complications after kidney transplantation-a prospective study on short-term outcomes. Transpl Int. 2019;32(1):66-74.
    Abstract DOI PMID Cited by ~47
  39. Nieuwenhuijs-Moeke GJ, van den Berg TAJ, Bakker SJL, van den Heuvel MC, Struys MMRF, Lisman T, et al. Preemptively and non-preemptively transplanted patients show a comparable hypercoagulable state prior to kidney transplantation compared to living kidney donors. PLoS One. 2018;13(7):e0200537.
    Abstract DOI PMID Cited by ~11
  40. Nieuwenhuijs-Moeke GJ, Nieuwenhuijs VB, Seelen MAJ, Berger SP, van den Heuvel MC, Burgerhof JGM, et al. Propofol-based anaesthesia versus sevoflurane-based anaesthesia for living donor kidney transplantation: results of the VAPOR-1 randomized controlled trial. Br J Anaesth. 2017;118(5):720-732.
    Abstract DOI PMID Cited by ~49
  41. Krogstrup NV, Oltean M, Nieuwenhuijs-Moeke GJ, Dor FJMF, Møldrup U, Krag SP, et al. Remote Ischemic Conditioning on Recipients of Deceased Renal Transplants Does Not Improve Early Graft Function: A Multicenter Randomized, Controlled Clinical Trial. Am J Transplant. 2017;17(4):1042-1049.
    Abstract DOI PMID Cited by ~46
  42. Kierulf-Lassen C, Nieuwenhuijs-Moeke GJ, Krogstrup NV, Oltean M, Jespersen B, Dor FJMF. Molecular Mechanisms of Renal Ischemic Conditioning Strategies. Eur Surg Res. 2015;55(3):151-83.
    Abstract DOI PMID Cited by ~25
  43. Krogstrup NV, Oltean M, Bibby BM, Nieuwenhuijs-Moeke GJ, Dor FJMF, Birn H, et al. Remote ischaemic conditioning on recipients of deceased renal transplants, effect on immediate and extended kidney graft function: a multicentre, randomised controlled trial protocol (CONTEXT). BMJ Open. 2015;5(8):e007941.
    Abstract DOI PMID Cited by ~19
  44. van Rijt WG, Nieuwenhuijs-Moeke GJ, van Goor H, Ottens PJ, Ploeg RJ, Leuvenink HGD. Renoprotective capacities of non-erythropoietic EPO derivative, ARA290, following renal ischemia/reperfusion injury. J Transl Med. 2013;11:286.
    Abstract DOI PMID Cited by ~18
  45. van Rijt WG, Nieuwenhuijs-Moeke GJ, van Goor H, Jespersen B, Ottens PJ, Ploeg RJ, et al. ARA290, a non-erythropoietic EPO derivative, attenuates renal ischemia/reperfusion injury. J Transl Med. 2013;11:9.
    Abstract DOI PMID Cited by ~31