Tuinhout RS, Jongman RM, Nieuwenhuijs-Moeke GJ, Abdulahad WH, Struys MMRF, van Meurs M, et al. Effects of sevoflurane, propofol, remifentanil, and fentanyl on the endothelial proinflammatory response: an in vitro exploratory study. Can J Anaesth. 2025;72(8):1291-1304.
Vulcano TJ, Abdulahad WH, van Meurs M, Jongman RM, Struys MMRF, Bosch DJ. The Impact of Different Anesthetics on the Distribution and Cytotoxic Function of NK Cell Subpopulations: An In Vitro Study. Int J Mol Sci. 2024;25(20).
Stern M, Kok WF, Doorduin J, Jongman RM, Jainandunsing J, Nieuwenhuijs-Moeke GJ, et al. Mild and deep hypothermia differentially affect cerebral neuroinflammatory and cold shock response following cardiopulmonary bypass in rat. Brain Behav Immun. 2024;119:96-104.
Steinkühler T, Yang S, Hu MA, Jainandunsing JS, Jager NM, Erasmus ME, et al. Ex Vivo Optimization of Donor Lungs with Inhaled Sevoflurane during Normothermic Ex Vivo Lung Perfusion (VITALISE): A Pilot and Feasibility Study in Sheep. Int J Mol Sci. 2024;25(4).
Cankar K, Van Laere K, Bosch D. Genome Editing for Reduction of Bitterness and for Production of Medicinal Terpenes in Cichorium Species. In: Ricroch A, Eriksson D, Miladinović D, Sweet J, Laere K, Woźniak-Gientka E, editors. A Roadmap for Plant Genome Editing. Cham: Springer Nature Switzerland; 2024. p. 373-384.
Stern M, Nieuwenhuijs-Moeke GJ, Absalom A, van Leeuwen B, van der Wal-Huisman H, Plas M, et al. Association between anaesthesia-related factors and postoperative neurocognitive disorder: a post-hoc analysis. BMC Anesthesiol. 2023;23(1):368.
Salvagnin U, Unkel K, Sprink T, Bundock P, Sevenier R, Bogdanović M, et al. A comparison of three different delivery methods for achieving CRISPR/Cas9 mediated genome editing in. Front Plant Sci. 2023;14:1111110.
Mindt M, Ferrer L, Bosch D, Cankar K, Wendisch VF. De novo tryptophanase-based indole production by metabolically engineered Corynebacterium glutamicum. Appl Microbiol Biotechnol. 2023;107(5-6):1621-1634.
Cankar K, Hakkert JC, Sevenier R, Campo E, Schipper B, Papastolopoulou C, et al. CRISPR/Cas9 targeted inactivation of the kauniolide synthase in chicory results in accumulation of costunolide and its conjugates in taproots. Front Plant Sci. 2022;13:940003.
Ávila-Gálvez MÁ, Rafael-Pita C, Fernández N, Baixinho J, Anastácio JD, Cankar K, et al. Targeting proteases involved in the viral replication of SARS-CoV-2 by sesquiterpene lactones from chicory (. Food Funct. 2022;13(17):8977-8988.
Mindt M, Kashkooli AB, Suarez-Diez M, Ferrer L, Jilg T, Bosch D, et al. Production of indole by Corynebacterium glutamicum microbial cell factories for flavor and fragrance applications. Microb Cell Fact. 2022;21(1):45.
Bosch DJ, Nieuwenhuijs-Moeke GJ, van Meurs M, Abdulahad WH, Struys MMRF. Immune Modulatory Effects of Nonsteroidal Anti-inflammatory Drugs in the Perioperative Period and Their Consequence on Postoperative Outcome. Anesthesiology. 2022;136(5):843-860.
Cankar K, Bundock P, Sevenier R, Häkkinen ST, Hakkert JC, Beekwilder J, et al. Inactivation of the germacrene A synthase genes by CRISPR/Cas9 eliminates the biosynthesis of sesquiterpene lactones in Cichorium intybus L. Plant Biotechnol J. 2021;19(12):2442-2453.
Nieuwenhuijs-Moeke GJ, Bosch DJ, Leuvenink HGD. Molecular Aspects of Volatile Anesthetic-Induced Organ Protection and Its Potential in Kidney Transplantation. Int J Mol Sci. 2021;22(5).
Girolamo AD, Durairaj J, van Houwelingen A, Verstappen F, Bosch D, Cankar K, et al. The santalene synthase from Cinnamomum camphora: Reconstruction of a sesquiterpene synthase from a monoterpene synthase. Arch Biochem Biophys. 2020;695:108647.
Bosch DJ, Meurs MV, Jongman RM, Heeringa P, Abdulahad WH, Struys MMRF. Effects of propofol and dexmedetomidine with and without remifentanil on serum cytokine concentrations in healthy volunteers: a post hoc analysis. Br J Anaesth. 2020;125(3):267-274.
Outchkourov NS, Karlova R, Hölscher M, Schrama X, Blilou I, Jongedijk E, et al. Transcription Factor-Mediated Control of Anthocyanin Biosynthesis in Vegetative Tissues. Plant Physiol. 2018;176(2):1862-1878.
Kytidou K, Beenakker TJM, Westerhof LB, Hokke CH, Moolenaar GF, Goosen N, et al. Human Alpha Galactosidases Transiently Produced in. Front Plant Sci. 2017;8:1026.
Bosch DJ, Wang D, Nijsten MWN, Mul VEM, Hospers GAP, Burgerhof JGM, et al. Longitudinal analysis of cytokine expression during neoadjuvant chemoradiotherapy and subsequent surgery in esophageal cancer patients. Am J Surg. 2016;212(1):89-95.
Cankar K, Jongedijk E, Klompmaker M, Majdic T, Mumm R, Bouwmeester H, et al. (+)-Valencene production in Nicotiana benthamiana is increased by down-regulation of competing pathways. Biotechnol J. 2015;10(1):180-9.
Raven N, Rasche S, Kuehn C, Anderlei T, Klöckner W, Schuster F, et al. Scaled-up manufacturing of recombinant antibodies produced by plant cells in a 200-L orbitally-shaken disposable bioreactor. Biotechnol Bioeng. 2015;112(2):308-21.
Outchkourov NS, Carollo CA, Gomez-Roldan V, de Vos RCH, Bosch D, Hall RD, et al. Control of anthocyanin and non-flavonoid compounds by anthocyanin-regulating MYB and bHLH transcription factors in Nicotiana benthamiana leaves. Front Plant Sci. 2014;5:519.
Westerhof LB, Wilbers RHP, van Raaij DR, Nguyen D, Goverse A, Henquet MGL, et al. Monomeric IgA can be produced in planta as efficient as IgG, yet receives different N-glycans. Plant Biotechnol J. 2014;12(9):1333-42.
Hesselink T, Rouwendal GJA, Henquet MGL, Florack DEA, Helsper JPFG, Bosch D. Expression of natural human β1,4-GalT1 variants and of non-mammalian homologues in plants leads to differences in galactosylation of N-glycans. Transgenic Res. 2014;23(5):717-28.
Scholtmeijer K, Cankar K, Beekwilder J, Wösten HAB, Lugones LG, Bosch D. Production of (+)-valencene in the mushroom-forming fungus S. commune. Appl Microbiol Biotechnol. 2014;98(11):5059-68.
Cankar K, van Houwelingen A, Goedbloed M, Renirie R, de Jong RM, Bouwmeester H, et al. Valencene oxidase CYP706M1 from Alaska cedar (Callitropsis nootkatensis). FEBS Lett. 2014;588(6):1001-7.
Beekwilder J, van Rossum HM, Koopman F, Sonntag F, Buchhaupt M, Schrader J, et al. Polycistronic expression of a β-carotene biosynthetic pathway in Saccharomyces cerevisiae coupled to β-ionone production. J Biotechnol. 2014;192 Pt B:383-92.
Beekwilder J, van Houwelingen A, Cankar K, van Dijk ADJ, de Jong RM, Stoopen G, et al. Valencene synthase from the heartwood of Nootka cypress (Callitropsis nootkatensis) for biotechnological production of valencene. Plant Biotechnol J. 2014;12(2):174-82.
Häkkinen ST, Raven N, Henquet M, Laukkanen M, Anderlei T, Pitkänen J, et al. Molecular farming in tobacco hairy roots by triggering the secretion of a pharmaceutical antibody. Biotechnol Bioeng. 2014;111(2):336-46.
Schoffelen S, Beekwilder J, Debets MF, Bosch D, van Hest JCM. Construction of a multifunctional enzyme complex via the strain-promoted azide-alkyne cycloaddition. Bioconjug Chem. 2013;24(6):987-96.
Berends E, Lehle L, Henquet M, Hesselink T, Wösten HAB, Lugones LG, et al. Identification of alg3 in the mushroom-forming fungus Schizophyllum commune and analysis of the Δalg3 knockout mutant. Glycobiology. 2013;23(2):147-54.
Koopman F, Beekwilder J, Crimi B, van Houwelingen A, Hall RD, Bosch D, et al. De novo production of the flavonoid naringenin in engineered Saccharomyces cerevisiae. Microb Cell Fact. 2012;11:155.
Song W, Henquet MGL, Mentink RA, van Dijk AJ, Cordewener JHG, Bosch D, et al. N-glycoproteomics in plants: perspectives and challenges. J Proteomics. 2011;74(8):1463-74.
Henquet M, Eigenhuijsen J, Hesselink T, Spiegel H, Schreuder M, van Duijn E, et al. Characterization of the single-chain Fv-Fc antibody MBP10 produced in Arabidopsis alg3 mutant seeds. Transgenic Res. 2011;20(5):1033-42.
Cankar K, van Houwelingen A, Bosch D, Sonke T, Bouwmeester H, Beekwilder J. A chicory cytochrome P450 mono-oxygenase CYP71AV8 for the oxidation of (+)-valencene. FEBS Lett. 2011;585(1):178-82.
van Herpen TWJM, Cankar K, Nogueira M, Bosch D, Bouwmeester HJ, Beekwilder J. Nicotiana benthamiana as a production platform for artemisinin precursors. PLoS One. 2010;5(12):e14222.
van den Broeck HC, de Jong HC, Salentijn EMJ, Dekking L, Bosch D, Hamer RJ, et al. Presence of celiac disease epitopes in modern and old hexaploid wheat varieties: wheat breeding may have contributed to increased prevalence of celiac disease. Theor Appl Genet. 2010;121(8):1527-39.
Henquet M, Heinhuis B, Borst JW, Eigenhuijsen J, Schreuder M, Bosch D, et al. Differential effects of human and plant N-acetylglucosaminyltransferase I (GnTI) in plants. Transgenic Res. 2010;19(4):535-47.
Berends E, Scholtmeijer K, Wösten HAB, Bosch D, Lugones LG. The use of mushroom-forming fungi for the production of N-glycosylated therapeutic proteins. Trends Microbiol. 2009;17(10):439-43.
Zhang M, Henquet M, Chen Z, Zhang H, Zhang Y, Ren X, et al. LEW3, encoding a putative alpha-1,2-mannosyltransferase (ALG11) in N-linked glycoprotein, plays vital roles in cell-wall biosynthesis and the abiotic stress response in Arabidopsis thaliana. Plant J. 2009;60(6):983-99.
Rouwendal GJA, Florack DEA, Hesselink T, Cordewener JH, Helsper JPFG, Bosch D. Synthesis of Lewis X epitopes on plant N-glycans. Carbohydr Res. 2009;344(12):1487-93.
Berends E, Ohm RA, de Jong JF, Rouwendal G, Wösten HAB, Lugones LG, et al. Genomic and biochemical analysis of N glycosylation in the mushroom-forming basidiomycete Schizophyllum commune. Appl Environ Microbiol. 2009;75(13):4648-52.
van den Broeck HC, van Herpen TWJM, Schuit C, Salentijn EMJ, Dekking L, Bosch D, et al. Removing celiac disease-related gluten proteins from bread wheat while retaining technological properties: a study with Chinese Spring deletion lines. BMC Plant Biol. 2009;9:41.
van den Broeck HC, America AHP, Smulders MJM, Bosch D, Hamer RJ, Gilissen LJWJ, et al. A modified extraction protocol enables detection and quantification of celiac disease-related gluten proteins from wheat. J Chromatogr B Analyt Technol Biomed Life Sci. 2009;877(10):975-82.
van Beelen VA, Spenkelink B, Mooibroek H, Sijtsma L, Bosch D, Rietjens IMCM, et al. An n-3 PUFA-rich microalgal oil diet protects to a similar extent as a fish oil-rich diet against AOM-induced colonic aberrant crypt foci in F344 rats. Food Chem Toxicol. 2009;47(2):316-20.
Henquet M, Lehle L, Schreuder M, Rouwendal G, Molthoff J, Helsper J, et al. Identification of the gene encoding the alpha1,3-mannosyltransferase (ALG3) in Arabidopsis and characterization of downstream n-glycan processing. Plant Cell. 2008;20(6):1652-64.
Rouwendal GJA, Wuhrer M, Florack DEA, Koeleman CAM, Deelder AM, Bakker H, et al. Efficient introduction of a bisecting GlcNAc residue in tobacco N-glycans by expression of the gene encoding human N-acetylglucosaminyltransferase III. Glycobiology. 2007;17(3):334-44.
van Beelen VA, Roeleveld J, Mooibroek H, Sijtsma L, Bino RJ, Bosch D, et al. A comparative study on the effect of algal and fish oil on viability and cell proliferation of Caco-2 cells. Food Chem Toxicol. 2007;45(5):716-24.
van Beelen VA, Aarts JMMJG, Reus A, Mooibroek H, Sijtsma L, Bosch D, et al. Differential induction of electrophile-responsive element-regulated genes by n-3 and n-6 polyunsaturated fatty acids. FEBS Lett. 2006;580(19):4587-90.
Bakker H, Rouwendal GJA, Karnoup AS, Florack DEA, Stoopen GM, Helsper JPFG, et al. An antibody produced in tobacco expressing a hybrid beta-1,4-galactosyltransferase is essentially devoid of plant carbohydrate epitopes. Proc Natl Acad Sci U S A. 2006;103(20):7577-82.
van Herpen TWJM, Goryunova SV, van der Schoot J, Mitreva M, Salentijn E, Vorst O, et al. Alpha-gliadin genes from the A, B, and D genomes of wheat contain different sets of celiac disease epitopes. BMC Genomics. 2006;7:1.
Spaenij-Dekking L, Kooy-Winkelaar Y, van Veelen P, Drijfhout JW, Jonker H, van Soest L, et al. Natural variation in toxicity of wheat: potential for selection of nontoxic varieties for celiac disease patients. Gastroenterology. 2005;129(3):797-806.
Gilissen LJWJ, Bolhaar STHP, Matos CI, Rouwendal GJA, Boone MJ, Krens FA, et al. Silencing the major apple allergen Mal d 1 by using the RNA interference approach. J Allergy Clin Immunol. 2005;115(2):364-9.
Bakker H, Routier F, Oelmann S, Jordi W, Lommen A, Gerardy-Schahn R, et al. Molecular cloning of two Arabidopsis UDP-galactose transporters by complementation of a deficient Chinese hamster ovary cell line. Glycobiology. 2005;15(2):193-201.
Helsper JPFG, Gilissen LJWJ, van Ree R, America AHP, Cordewener JHG, Bosch D. Quadrupole time-of-flight mass spectrometry: a method to study the actual expression of allergen isoforms identified by PCR cloning. J Allergy Clin Immunol. 2002;110(1):131-8.
Krebbers E, Bosch D, Vandekerckhove J. Production of foreign proteins and peptides in transgenic plants. In: Beek T, Breteler H, editors. Phytochemistry and Agriculture. Oxford University PressOxford; 1993. p. 346-355.